3- or 4-substituted piperidine compounds

Details 3- or 4-substituted piperidine compounds 3- or 4-substituted piperidine compounds

C - Chemistry, Metallurgy

07

D

C07D 257/04 (2006.01) A61K 31/445 (2006.01) C07D 257/02 (2006.01)

Patent

CA 2725742

There are disclosed racemic or enantiomerically enriched 3- or 4-substituted piperidine compounds represented by the following structural formula (I) or any of their isomers, or pharmaceutically acceptable salts thereof Also disclosed are pharmaceutical compositions containing the subject compounds The subject compounds are useful for the treatment of diseases of the central nervous system, particularly depression, anxiety and pam disorder.

La présente invention concerne des composés de pipéridine à substitution 3 ou 4 racémiques ou énantiomériquement enrichis qui sont représentés par la formule développée (I) ou un de leurs isomères ou de leurs sels pharmaceutiquement acceptables. Cette invention porte également sur des compositions pharmaceutiques contenant lesdits composés. Les composés selon l'invention sont utiles pour le traitement de maladies du système nerveux central, notamment la dépression, les troubles anxieux et douloureux.

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