3-(or 5-) trifluoromethyl-1-aryl pyrazoles

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

260/315.3, 260/3

C07D 231/12 (2006.01) C07D 403/00 (2006.01) C07D 409/04 (2006.01)

Patent

CA 1130808

Abstract of the Disclosure 3-(or 5-) Trifluoromethyl-1-aryl pyrazoles of the formulae 1 and 2 Image Image 1 2 in which Ar is optionally mono-or di-substituted phenyl or naphthyl and R1 is optionally mono-or di-substituted phenyl, naphthyl, thienyl, or furyl, The compounds possess anti- inflammatory, analgesic, and anti-pyretic activities and have a low order of toxicity. Methods for their preparation and use are also disclosed.

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