3-oxadiazole and 3-carboxylic acid .beta.-carboline...

Details 3-oxadiazole and 3-carboxylic acid .beta.-carboline... 3-oxadiazole and 3-carboxylic acid .beta.-carboline...

C - Chemistry, Metallurgy

07

D

167/231, 260/276

C07D 471/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 1332836

Compounds of formula I Image (I) wherein X is COOR3 or an oxadiazolyl radical of the formula or R2 is H, lower alkyl or cycloalkyl, R3 is lower alkyl, R4 is hydrogen, lower alkyl or lower alkoxyalkyl, RA is -CHR1-Z-R5, Z is sulfur or oxygen, R1 is lower alkyl or optionally substituted phenyl, and R5 is hydrogen, phenyl or optionally substituted lower alkyl, and wherein each compound can contain 1 or 2 RA radicals have valuable pharmacological properties.

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