3-oxaprostaglandins

Details 3-oxaprostaglandins 3-oxaprostaglandins

C - Chemistry, Metallurgy

07

C

260/235.01

C07C 59/90 (2006.01) C07C 45/59 (2006.01) C07C 405/00 (2006.01) C07D 307/42 (2006.01) C07D 407/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1221962

3-OXAPROSTAGLANDINS ABSTRACT This invention relates to novel 3-oxa-15-desoxy-16- hydroxy-16-alkyl prostaglandins of the E2 series and the 5,6-acetylene derivatives thereof. These compounds are useful for their gastric antisecretory, cytoprotective, antiulcer, and antihypertensive activity. In addition the invention also discloses certain novel trialkylsilyl acetylenic intermediates.

446549

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