3'-oxygenated derivatives of 4'-deoxy vlb "a" and "b" and...

Details 3'-oxygenated derivatives of 4'-deoxy vlb "a" and "b" and... 3'-oxygenated derivatives of 4'-deoxy vlb "a" and "b" and...

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1097628

Abstract of the Disclosure 3'-hydroxy and 3'-keto derivatives of 4'-deoxy VLB (deoxy VLB "A"), 4'-deoxyleurosidine (deoxy VLB "B"), 4'-deoxyvincristine and 4'-deoxy-1-desmethyl-1-formylleuro- sidine and related 4-desacetyl and C-3 carboxamide deriva- tives, useful as anti-tumor agents in mammals are pre- pared from tbe starting material leurosine. X-4739

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