3-phenyl-1-propanones, process of preparing thereof and...

Details 3-phenyl-1-propanones, process of preparing thereof and... 3-phenyl-1-propanones, process of preparing thereof and...

C - Chemistry, Metallurgy

07

D

167/207, 260/279

C07D 333/32 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1298832

ABSTRACT OF THE DISCLOSURE Therapeutically useful 1-[3-(2-dialkylaminoethoxy)- 2-thienyl]-3-phenyl-1-propanones of the formula Image (I) and acid addition salts thereof, wherein R and R1 each are hydrogen or methyl, R2 and R3, which are the same or different, each are alkyl, cycloalkyl, alkenyl or alkynyl each containing up to 8 carbon atoms, or R2 and R3 together with the nitrogen atom to which they are attached form a 5 to 7-membered saturated ring or a saturated heterocyclic ring which may contain optionally an oxygen or nitrogen atom as further hetero atom in the ring, a further nitrogen atom being unsubstituted or substituted by an alkyl radical containing 1 to 3 carbon atoms. The compounds are useful for the treatment of various disturbances of the heart rhythm.

531928

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