C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/18 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/46 (2006.01) C07D 471/08 (2006.01) C07D 471/10 (2006.01)
Patent
CA 2391915
Pharmacologically active compounds of the general formula I (see formula I) wherein R1 is an alkyl group with 1 - 6 carbon atoms or a cycloalkylalkyl group with 4 - 7 carbon atoms, R2 is lower alkyl and R3 is lower alkyl or R2 and R3 together form an alkylene chain with 3 - 6 carbon atoms, R4 stands for a phenyl radical monosubstituted in the ortho or para position by nitro, cyano or lower alkanoyl or disubstituted in the ortho and para position by nitro, and their physiologically compatible acid addition salts are described.
Des composés pharmacologiquement actifs ayant la formule générale I (voir la formule I) où R1 est un groupe alkyle muni de 1 à 6 atomes de carbone ou un groupe cycloalkylalkyle muni de 4 à 7 atomes de carbone, R2 est un alkyle de petite taille et R3 est un alkyle de petite taille ou R2 et R3 ensemble forment un chaîne alcényle munie de 3 à 6 atomes de carbone, R4 représente un radical phényle monosubstitué en position ortho ou para par un groupe nitro, un groupe cyano ou un alcanoyle de petite taille ou disubstitué en position ortho et para par un groupe nitro, et leurs sels d'addition acide physiologiquement compatibles sont décrits.
Brueckner Reinhard
Messinger Josef
Schoen Uwe
Ziegler Dieter
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Solvay Pharmaceuticals Gmbh
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