3-phenylureido-azepin-2-ones and benzazepin-2-ones useful as...

C - Chemistry – Metallurgy – 07 – D

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C07D 223/10 (2006.01) A61K 31/55 (2006.01) C07D 223/16 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2117367

2117367 9315059 PCTABS00024 The present invention relates to novel substituted hexahydroazepinones and tetrahydrobenzazepinones of formulae (I) and (II) wherein R1, Z1, Z2, Y1 and Y2 are as defined, and to novel intermediates used in the synthesis of such compounds. Such compounds are useful in the treatment and prevention of gastrointestinal disorders, pain and anxiety disorders.

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