C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2223062
Novel 3-pyridyloxymethyl heterocyclic ether compounds having formula (I), wherein * is a chiral center and n, X, R1, R2, A andB are specifically defined, which are useful in controlling chemical synaptic transmission; therapeutically-effective pharmaceutical compositions therof; and use of said compositions to selectively control synaptic transmission in mammals.
Divulgation de nouveaux éthers hétérocycliques pyrid-3-yloxyméthyliques de formule (I), dans laquelle * signifie un centre chiral et n, X, R1, R2, A et B sont définis de manière spécifique. Lesdits composés sont utiles pour réguler la transmission synaptique chimique. Divulgation aussi des compositions pharmaceutiques de ces composés efficaces sur le plan thérapeutique, et de l'utilisation desdites compositions pour réguler de manière sélective la transmission synaptique chez les mammifères.
He Yun
Holladay Mark W.
Lin Nan-Horng
Ryther Keith B.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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