3-(substituted)-1-carba (dethia)-3-cephems and...

Details 3-(substituted)-1-carba (dethia)-3-cephems and... 3-(substituted)-1-carba (dethia)-3-cephems and...

C - Chemistry, Metallurgy

07

D

260/100, 167/187

C07D 463/16 (2006.01) A61K 31/545 (2006.01) C07D 463/00 (2006.01) C07D 501/16 (2006.01)

Patent

CA 1338571

Cephalosporin and 1-carba(1-dethia)ceph- alosporin antibiotics substituted in the 3-position with, inter alia, alkyl, alkenyl and alkynyl, are provided via a process comprising conversion of a cephalosporin or 1-carba(1-dethia)-3-cephem sub- stituted in the 3-position with halogen or a sulfonyloxy ester with Pd(O) mediated alkylation with organostannanes.

594273

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