C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 407/04 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2723279
The invention relates to 3-substituted-1H-indole compounds of the Formula (I): or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds for the treatment of PI3 and mTOR kinase- mediated diseases, e.g. cancer.
Cette invention concerne des composés de 1H-indole 3 substitués représentés par la formule 1, ou bien un sel de ces composés de qualité pharmaceutique. Elle concerne également les variables des constituants comme définies dans le descriptif, des compositions renfermant les composés et des procédés de fabrication de ces composés.
Anderson James Thomas
Ayral-Kaloustian Semiramis
Birnberg Gary Harold
Brooijmans Natasja
Bursavich Matthew Gregory
Torys Llp
Wyeth Llc
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