3-substituted-2-(aminocarboxyl)-oxiranecarboxylic acid...

Details 3-substituted-2-(aminocarboxyl)-oxiranecarboxylic acid... 3-substituted-2-(aminocarboxyl)-oxiranecarboxylic acid...

C - Chemistry, Metallurgy

07

D

167/207, 260/369

C07D 303/48 (2006.01) A61K 31/335 (2006.01)

Patent

CA 1142523

ABSTRACT OF THE DISCLOSURE This invention relates to oxiranecarboxylic acid ester derivatives. There are provided 3-substituted-2-(aminocarbonyl)- oxiranecarboxylic acid esters of formula Image (I) wherein R is phenyl substituted by one or two groups independently selected from nitro and alkoxy or is benzoyl, R3 is alkyl, alkenyl, alkynyl or cycloalkyl, R1 and R2 are each independently hydrogen, alkyl, alkenyl, alkynyl or cycloalkyl or R1 and R2 together repre- sent an alkylene chain containing four or five carbon atoms; pro- cesses for their preparation; lipogenesis-inhibiting compositions containing them and the preparation of such compositions. Oxirane carboxylic acid ester derivatives of formula I have exhibited lipogenesis inhibiting activity, and thus find use in animal husbandry to provide a leaner carcass after slaughter.

348274

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