3-substituted (3-phenyl)-propionic acid derivatives for the...

Details 3-substituted (3-phenyl)-propionic acid derivatives for the... 3-substituted (3-phenyl)-propionic acid derivatives for the...

C - Chemistry, Metallurgy

07

D

C07D 233/54 (2006.01) A61K 31/41 (2006.01) A61K 31/4164 (2006.01) A61K 31/4196 (2006.01) A61K 31/421 (2006.01) A61K 31/427 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 249/08 (2006.01) C07D 257/04 (2006.01) C07D 263/32 (2006.01) C07D 277/24 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2607848

The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I: wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and R1 has the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.

La présente invention concerne des composés utiles, par exemple, pour moduler les taux d'insuline chez un sujet, lesdits composés étant représentés par la formule (I), dans laquelle Q représente un phényle facultativement substitué; L représente une liaison ou O; P représente un anneau benzène ou thiazole facultativement substitué; et les valeurs de R1 sont les valeurs spécifiées dans l'invention. Cette invention porte également sur des compositions, des utilisations et des méthodes d'utilisation de ces composés, par exemple, pour le traitement du diabète de type II. Formule (I)

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