3-substituted-5- and 6-aminoalkyl indole-2-carboxylic acid...

Details 3-substituted-5- and 6-aminoalkyl indole-2-carboxylic acid... 3-substituted-5- and 6-aminoalkyl indole-2-carboxylic acid...

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 25/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2577667

The present invention discloses and claims compounds of formula (I) and formula (II) as inhibitors of human casein kinase I.epsilon., and methods of using said compounds of formula (I) and formula (II) for treating central nervous system diseases and disorders including mood disorders and sleep disorders. Pharmaceutical compositions comprising compounds of formula (I) or formula (II) are also disclosed and claimed.

La présente invention concerne la description et les revendications de composés en tant qu~inhibiteurs de la caséine kinase i epsilon humaine, et des procédés d~utilisation desdits composés pour le traitement de maladies et de troubles du système nerveux central y compris des troubles de l~humeur et des troubles du sommeil. Il est également décrit et revendiqué des compositions pharmaceutiques.

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