3-substituted-5-phenyl-5-pyridyl hydantoins

C - Chemistry – Metallurgy – 07 – D

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260/278.2

C07D 401/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 1084057

3-SUBSTITUTED-5-PHENYL-5-PYRIDYL HYDANTOINS ABSTRACT Compounds having the generic structure, Image , and their nontoxic, pharmacologically acceptable salts are useful in the chemotherapy of arrhythmias in individuals for whom such therapy is indicated. In the preceding structural formula: R1 is a 2-pyridyl, 3-pyridyl, or 4-pyridyl radical; n is an integer of the set 1-3; and R2 is a hydrogen atom, a hydroxyl, or an equivalent alkoxyl group having from 1 to 3 carbon atoms.

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