3-substituted 6,7-dihydroxytetrahydroisoquinoline...

Details 3-substituted 6,7-dihydroxytetrahydroisoquinoline... 3-substituted 6,7-dihydroxytetrahydroisoquinoline...

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61P 31/04 (2006.01) C07D 217/02 (2006.01) C07D 217/12 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01)

Patent

CA 2458477

The invention relates to novel tetrahydroisoquinoline derivatives of general formula I and theirs use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and their use as anti- infectives, wherein R1, R2 and R3 are as defined in claim 1.

La présente invention concerne de nouveaux dérivés de tétrahydroisoquinoline de formule générale (1), ainsi que leur utilisation en tant qu'ingrédients actifs dans la préparation de compositions pharmaceutiques. La présente invention concerne également des aspects liés à ces dérivés, tels que des procédés pour préparer lesdits composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés et, notamment, leur utilisation en tant qu'agents anti-infectieux. Dans cette formule (1), R?1¿, R?2¿ et R?3¿ sont tels que définis dans la revendication 1.

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