3-substituted nitro-steroid derivatives as...

Details 3-substituted nitro-steroid derivatives as... 3-substituted nitro-steroid derivatives as...

C - Chemistry, Metallurgy

07

J

260/18, 167/191,

C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2023610

ABSTRACT OF THE DISCLOSURE 3-SUBSTITUTED NITRO-STEROID DERIVATIVES AS 5-.alpha.-REDUCTASE INHIBITORS Invented are 3-nitro- substituted steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase including using these compounds to reduce prostate size. Also invented are intermediates used in preparing these compounds.

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