3-substituted vinyl cephalosporin derivatives

Details 3-substituted vinyl cephalosporin derivatives 3-substituted vinyl cephalosporin derivatives

C - Chemistry, Metallurgy

07

D

260/101, 167/187

C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2021025

ABSTRACT 3-Substituted vinyl cephalosporin derivatives represented by the following formula: Image wherein R1 represents a hydroxyl or lower alkoxyl group, X represents a nitrogen atom or a group represented by the formula -CH=, R2 represents a car- boxyl group or a carboxyl group protected with a pro- tecting group, and R3 is as defined herein, and pharmaceutically acceptable salts thereof are potent antibacterial agents. Processes for their preparation, intermediates in such processes, and antibacterial com- positions containing them as active ingredients are also described.

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