3-tetrahydronaphthyl-4-hydroxycoumarin compounds having...

C - Chemistry – Metallurgy – 07 – D

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167/11, 260/358,

C07D 311/56 (2006.01) A01N 43/16 (2006.01) C07D 405/02 (2006.01)

Patent

CA 1232908

K 1870 Abstract Compounds having blood-anticoagulant properties of the general molecular formula: Image (II) , in which Z represents a halogen atom, preferably a chlorine atom, and n is 0, 1 or 2 and R4 represents either (1) a grouping which ccmprises a phenylene radical attached directly or indirectly to the tetralin ring and having in the para position (with respect to such attachment) an electron-withdrawing atom or group whose rotational volume substantially does not exceed that of a phenyl group and which forms together with said phenylene radical a polarisable structure, or (2) a grouping selected from: Image or Image or Image BN23.006 or (3) a grouping which comprises a phenylene radical attached directly to the tetralin ring and having in the para position (with respect to such attachment) a substituted furanyl or thiophenyl radical attached thereto directly or through oxygen and/or methylene, said furanyl or thiophenyl radical having such an electron-withdrawing atom or group as a substituent in a position forming with the furanyl or thiophenyl radical a polarisable structure, Compounds of the type (1) in which R4 contains two phenylene radicals linked essentially linearly by an aliphatic chain comprising a methylene radical or radicals and optionally at least one oxygen or sulphur atom being preferred. Also included are the processes for the preparation of such compound; rodenticidal compositions containing them; and a method for controlling rodents by applying such a composition. BN11.008

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