3-tetrahydropyridin-4-yl indoles for treatment of psychotic...

Details 3-tetrahydropyridin-4-yl indoles for treatment of psychotic... 3-tetrahydropyridin-4-yl indoles for treatment of psychotic...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/4439 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2346896

The invention relates to a novel group 3-tetrahydropyridin-4-yl indoles having interesting pharmacological properties. These compounds have general formula (I) wherein: Ri is halogen, CF3, alkyl (1-3C), alkoxy (1-3C), CN or SCH3; m the value 0, 1 or 2; R2 is H or alkyl (1-3C); n has the value 3, 4, 5 or 6; R3 is halogen, alkyl (1- 4C); or alkoxy (1-4C); p has the value 0, 1, or 2 and salts thereof.

La présente invention concerne un nouveau groupe 3-tetrahydropyridin-4-yl indoles présentant d'intéressantes propriétés pharmacologiques. Ces composés sont représentés par la formule générale (I), dans laquelle R1 représente halogène, CF3, alkyle (1-3C), alcoxy (1-3C), CN ou SCH3; la valeur de m est 1, 2 ou 3; R2 représente H ou alkyle (1-3C); la valeur de n est 3, 4, 5 ou 6; R3 représente halogène, alkyle (1-4C) ou alcoxy (1-4C); la valeur de p étant 0, 1 ou 2. Cette invention concernant également des sels de ces composés.

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