3-vinyl- and 3-ethinyl-.beta.carbolines their production and...

Details 3-vinyl- and 3-ethinyl-.beta.carbolines their production and... 3-vinyl- and 3-ethinyl-.beta.carbolines their production and...

C - Chemistry, Metallurgy

07

D

167/211, 260/276

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01)

Patent

CA 1266049

ABSTRACT OF THE DISCLOSURE Compounds of formula I Image wherein: R1 is hydrogen or a protecting group; R2 is -CH=CR42 or -C=CR4; R4 is hydrogen or halogen; R3 is hydrogen, lower alkyl, or lower alkoxyalkyl; RA is, inter alia, hydrogen , OR7, lower alkyl, which optionally is substituted with aryl, lower alkoxy or NR5R6, R5 and R6 can be the same or different and in each case is hydrogen, lower alkyl or together with the nitrogen atom a 5-6 member ring, which can contain another heteratom, R7 is lower alkyl, optionally substituted aryl or aralkyl, and each compound can contain one or more RA radicals which are not hydrogen, have valuable pharmacological properties.

519907

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