35/31 kda subunit of the entamoeba histolytica adherence lectin

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/30 (2006.01) A61K 31/70 (2006.01) A61K 39/002 (2006.01) C07K 14/44 (2006.01) C07K 16/20 (2006.01) C07K 19/00 (2006.01) C12N 1/10 (2006.01) C12N 1/36 (2006.01) C12N 5/12 (2006.01) C12N 15/62 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2157599

The 35/31 kDa subunit of the Gal/GalNAc lectin and DNA encoding this protein in various strains of E. histolytica are provided. These materials are useful in vaccines and diagnostic assays, and in antisense methods to interrupt the production of the Gal/GalNAc lectin. Antibodies specific for the 35/31 kDa subunit also are disclosed.

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