36- derivatives of rifamycins

Details 36- derivatives of rifamycins 36- derivatives of rifamycins

C - Chemistry, Metallurgy

07

D

C07D 498/08 (2006.01) C07D 213/80 (2006.01) C07D 401/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2549561

An intermediate of general formula: (see formula I) for preparing rifamycin antibiotic derivatives, wherein Y, R6 and R7 independently are H or (C1-C4) alkyl, and R3 is (C1-C4) alkyl or (C3-C6) cycloalkyl; or R6 and R7 together with the adjacent nitrogen atom form a five or six membered heterocyclic ring, optionally containing one further heteroatom selected from the group consisting of an oxygen atom, a nitrogen atom and a sulfur atom, wherein one of the carbon or nitrogen atoms of the ring is optionally substituted by a (C1-C4)alkyl moiety; and an alkali metal salt thereof.

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