3h-imidazo [4, 5 -c] pyridine- 6 -carboxamides as anti-...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2753149

The present invention relates to compounds of general formula (I) in which A, L, M, Q1, Q3, Q4, R1, R5, R a, R b, R c, W, X, Y, Z1, Z2, Z3 are defined in the description, the salts thereof, particularly the physiologically acceptable salts thereof. The compounds are of potential utility in the treatment and/or prevention of inflammatory diseases and associated conditions, in particular, in the treatment and/or prevention of pain. The invention also relates to the use of such compounds as medicaments, to pharmaceutical compositions containing them, and to their preparation.

La présente invention concerne des composés de formule générale (I) dans laquelle A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 sont définis dans la description, leurs sels, particulièrement leurs sels physiologiquement acceptables. Les composés sont d'une utilité potentielle dans le traitement et/ou la prévention de maladies inflammatoires et d'affections associées, en particulier, dans le traitement et/ou la prévention de la douleur. L'invention concerne également l'utilisation de ces composés sous la forme de médicaments, de compositions pharmaceutiques les contenant et leur préparation.

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