C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/88 (2006.01) G01N 33/50 (2006.01) C07K 14/35 (2006.01) C12N 15/31 (2006.01) C12N 15/60 (2006.01) C12N 15/63 (2006.01) C12Q 1/527 (2006.01)
Patent
CA 2677734
The invention relates to (3R)-hydroxyacyl-ACP dehydratase enzymes used in the biosynthesis of mycolic acids, and to the use of same for screening antibiotics, medicaments that can be used to treat infections in humans or in animals, caused by Corynebacterineae, more specifically infections caused by pathogenic mycobacteria (Mycobacterium tuberculosis, M. africanum, M. leprae, M. ulcerans, M. microti, M. bovis, M. abscissus, M. avium, M. fortuitum, M. kansasii...), and infections caused by other genres such as Nocardia, Rhodococcus, Gordona...
Enzymes (3R)-hydroxyacyl-ACP déshydratases impliquées dans la biosynthèse des acides mycoliques et leur utilisation pour le criblage d'antibiotiques, médicaments susceptibles d'être utilisés pour traiter des infections chez l'homme ou chez l'animal, dues à des Corynebacterineae et plus particulièrement des infections dues à des mycobactéries pathogènes (Mycobacterium tuberculosis, M. africanum, M. leprae, M. ulcerans, M. microti, M. bovis, M. abscissus, M. avium, M. fortuitum, M. kansasii...) ainsi que des infections provoquées par d'autres genres tels que Nocardia, Rhodococcus, Gordona...
Baeckbro Kristina
Daffe Mamadou
Jones Thomas Alwyn
Quemard Annaik
Sacco Emmanuelle
Centre National de La Recherche Scientifique
Robic
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