4-1 bb ligand in inflammatory diseases

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) C07K 14/705 (2006.01) C12N 15/11 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2666306

The invention provides 4-IBBL blocking agents, as well as pharmaceutical compositions and articles of manufacture comprising such blocking agents as new therapeutic interventions for sustained inflammation. Thus, the invention also provides methods for reducing sustained production of tumor necrosis factor.

La présente invention concerne des agents de blocage 4- IBBL, ainsi que des compositions pharmaceutiques et des articles manufacturés comprenant de tels agents de blocage en tant que nouveaux moyens thérapeutiques pour l'inflammation permanente. Cette invention concerne également des méthodes permettant de réduire la production soutenue du facteur de nécrose des tumeurs.

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