4,1-benzoxazepines and thia analogues thereof

Details 4,1-benzoxazepines and thia analogues thereof 4,1-benzoxazepines and thia analogues thereof

C - Chemistry, Metallurgy

07

D

260/238.5

C07D 267/14 (2006.01) C07D 249/08 (2006.01) C07D 249/10 (2006.01) C07D 273/00 (2006.01) C07D 285/36 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1127639

4,1-BENZOXAZEPINES AND THIA ANALOGS THEREOF ABSTRACT 4,1-Benzoxazepines and thia analogs thereof of the formula: Image (wherein -A-B- is the following group; Image , or Image (wherein R1 is hydrogen, C1 to C3 alkyl, or C7 to C9 aralkyl; R2 is C1 to C3 alkyl or C1 to C3 .alpha.-aminoalkyl; R3 is C2 to C6 dialkylamino; R4 is C2 to C6 dialkylamino or C5 to C7 alkylpiperazino; R5 is C1 to C3 alkyl; and Q is oxygen or sulfur); D is oxygen or sulfur; X is halogen or nitro; Y is hydrogen or halogen; and Z is hydrogen, C1 to C3 alkoxy, or C3 to C9 dialkylamino- alkoxy; with proviso that when -A-B- is Image , Z is not hydrogen). being useful as novel central nervous system drugs are prepared in various synthetic routes.

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