4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1-...

Details 4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1-... 4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1-...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01)

Patent

CA 2236545

A 4,10 beta -diacetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate, and the preparation thereof by crystallisation from a water-alcohol or water-ketone solution, are disclosed.

Dihydrate de (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phénylpropionate de 4,10.beta.-diacétoxy-2.alpha.-benzoyloxy-5,6,20-époxy-1- hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ène-13.alpha.-yle et sa préparation par cristallisation à partir d'une solution hydro-alcoolique ou hydro-cétonique.

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