4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compounds

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 211/22 (2006.01) A61K 31/4409 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2742105

The invention relates to compounds of formula (I) where a, R1, and R3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

La présente invention concerne des composés de formule (I) où a, R1, et R3-6 sont tels que définis dans la spécification, ou un sel pharmaceutiquement acceptable de ceux-ci. Les composés de formule (I) sont des inhibiteurs de recaptage de sérotonine et de norépinéphrine. Linvention concerne en outre des compositions pharmaceutiques comprenant de tels composés ; des procédés dutilisation de tels composés ; et un procédé et des intermédiaires pour préparer de tels composés.

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