4-(2-keto-1-benzimidazolinyl)piperidine compounds as...

Details 4-(2-keto-1-benzimidazolinyl)piperidine compounds as... 4-(2-keto-1-benzimidazolinyl)piperidine compounds as...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/445 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2317462

A compound of formula (I) or the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined above are useful as ORL1-receptor agonists, and useful as analgesics or the like in mammalian subjects.

Cette invention se rapporte à un composé représenté par la formule (I) ou aux sels de ce composé acceptables sur le plan pharmaceutique, formule dans laquelle R<1>, R<2>, R<3>, R<4> et R<5> sont présentés dans les pièces descriptives de l'invention. Ce composé ou ses sels sont utiles comme agonistes du récepteur ORL1 et peuvent servir d'analgésiques ou similaires chez des sujets mammifères.

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