4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]...

Details 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]... 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]...

C - Chemistry, Metallurgy

07

D

167/242, 260/328

C07D 495/04 (2006.01) A61K 31/38 (2006.01)

Patent

CA 2022118

10/WHN4 17906 TITLE OF THE INVENTION 4-(2-METHYL-2-HYDROXYPROPYLAMINO)-5,6-DIHYDROTHIENO- [2,3-B]THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE ABSTRACT OF THE DISCLOSURE 4-(2-Methyl-2-hydroxypropylamino)-5,6-dihy- drothieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropyl- amino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfon- amide-7,7-dioxide and is itself an active carbonic anhydrase inhibitor useful in the treatment of ocular hypertension by topical administration.

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