4-[3-(aryloxy)benzylidene]-3-methyl piperidine 5-membered...

Details 4-[3-(aryloxy)benzylidene]-3-methyl piperidine 5-membered... 4-[3-(aryloxy)benzylidene]-3-methyl piperidine 5-membered...

C - Chemistry, Metallurgy

07

D

C07D 211/70 (2006.01) A61K 31/4427 (2006.01) A61K 31/445 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2717087

The present invention relates to compounds of Formula (I), wherein Ar is a 5- membered heteroaryl moiety and X, Y and Z are independently N or CH; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.

La présente invention concerne des composés de formule (I), dans laquelle Ar est une fraction hétéroaryle à 5 éléments et X, Y et Z sont indépendamment N ou CH, ou un sel pharmaceutiquement acceptable correspondant, des procédés de préparation de ces composés, des produits intermédiaires utilisés dans la préparation de ces composés, des compositions contenant ces composés ainsi que les utilisations desdits composés pour traiter des maladies ou des affections associées à l'activité de l'hydrolase des amides d'acides gras (FAAH).

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