4-[3-(aryloxy)benzylidene]-3-methyl piperidine aryl...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/395 (2006.01) C07D 211/70 (2006.01) C07D 401/12 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2716886

The present invention relates to compounds of Formula (I), wherein Ar is optionally substituted phenyl or het-eroaryl and X, Y and Z are independently N or CH; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.

La présente invention concerne des composés de formule (I), dans laquelle Ar est éventuellement phényle ou hétéroaryle substitué et X, Y et Z sont indépendamment N ou CH, ou un sel pharmaceutiquement acceptable correspondant, des procédés de préparation de ces composés, des produits intermédiaires utilisés dans la préparation de ces composés, des compositions contenant ces composés ainsi que les utilisations desdits composés pour traiter des maladies ou des affections associées à l'activité de l'hydrolase des amides d'acides gras (FAAH).

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