4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoi...

Details 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoi... 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoi...

C - Chemistry, Metallurgy

07

D

C07D 231/14 (2006.01) A61K 31/415 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2703781

4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol- 1 -yl]benzoic acid and pharmaceutically-acceptable salts thereof and a particular crystalline form of the Agent (Form 1); their use in the inhibition of 11 .beta.HSD1, processes for making them and pharmaceutical compositions comprising them are also described.

L'invention concerne un acide 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoïque et sur des sels pharmaceutiquement acceptables de celui-ci ainsi que sur une forme cristalline particulière de l'agent (Forme 1). Elle concerne également leur utilisation dans l'inhibition de 11 ßHSD1, des procédés permettant de les fabriquer et sur des compositions pharmaceutiques les comprenant.

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