4,4' [9h-fluoren-9-ylidenebis (methylene)]-bispyrimidine for...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/26 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2073694

2073694 9110433 PCTABS00006 A fluorene compound, 4,4'-[9H-fluoren-9-ylidenebis(methylene)]bispyrimidine, or a pharmaceutically acceptable salt thereof, is useful in treating various neurological disorders in mammals. This compound has efficacy over a broad dosage range as measured by hypoxia induced cognition impairment and has a wide safety margin as measured by the ratio of cognition to the onset of overt symptoms.

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