4,4-diphenylcyclohexylpiperidine compounds and analogs thereof

C - Chemistry – Metallurgy – 07 – D

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260/279.4, 260/2

C07D 401/04 (2006.01) C07D 211/52 (2006.01) C07D 211/66 (2006.01) C07D 471/10 (2006.01)

Patent

CA 1074319

ABSTRACT OF THE DISCLOSURE 4,4-Diphenylcyclohexylpiperidine compounds and their analogs of the formula: Image wherein the dotted line in Ring A indicates an optional bond; R1, R2, R3 and R4 are independently a hydrogen atom, a halogen atom, a trifluoromethyl group or a lower alkyl group; n is 1 or 2; m is 0 or 1; and Am is a piperidino group of the formula: Image , Image Image where R5 and R6 are independently a hydrogen atom, a halogen atom, a trifluoromethyl group or a lower alkyl group, and the dotted line in Ring B indicates an optional bond; and pharmaceutically acceptable salts thereof are disclosed. They exhibit potent and long-lasting psychotropic effects.

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