4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 265/18 (2006.01) A61K 31/535 (2006.01) C07B 59/00 (2006.01) C07C 213/00 (2006.01) C07D 213/75 (2006.01) C07D 265/24 (2006.01) C07D 339/08 (2006.01) C07D 413/04 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2268953

The present invention relates to benzoxazinones of formula I, or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

La présente invention se rapporte à des benzoxazinones représentées par la formule (I), à des mélanges, formes stéréoisomères ou sels pharmaceutiquement acceptables de ces composés, qui s'avèrent utiles en tant qu'inhibiteurs de la transcriptase inverse du VIH. L'invention se rapporte à des compositions pharmaceutiques et à des kits diagnostiques contenant ces composés, à des procédés d'utilisation de ces compositions pour le traitement d'infections virales ou en tant que réactif de dosage, ainsi qu'à des intermédiaires et à des procédés de fabrication correspondants.

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