4,4-disubstituted piperdines

Details 4,4-disubstituted piperdines 4,4-disubstituted piperdines

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/538 (2006.01)

Patent

CA 2699889

The application relates to 4,4-disub-stituted piperidinesof the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R2, has the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.

L'invention se rapporte : à des pipéridines 4,4-disubstituées de la formule générale (I) et à leurs sels, de préférence leurs sels pharmaceutiquement acceptables, où R2 est tel que défini dans la description; à un procédé de préparation de ces dernières; et à l'utilisation de ces composés comme médicaments, en particulier comme inhibiteurs de la rénine.

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