4,4-disubstituted piperidines

Details 4,4-disubstituted piperidines 4,4-disubstituted piperidines

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/538 (2006.01) A61P 9/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2703593

The application relates to 4,4-disubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R2, has the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.

L'invention porte sur des pipéridines 4,4-disubstituées représentées par la formule générale (I) et sur leurs sels, de préférence leurs sels pharmaceutiquement acceptables. Dans la formule (I), R2 a les significations expliquées dans la description. L'invention porte également sur un procédé de préparation de ces pipéridines et sur l'utilisation de ces composés comme médicaments, en particulier comme inhibiteurs de la rénine.

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