4-(4-fluorophenylmethyl)-piperidines having sigma and...

Details 4-(4-fluorophenylmethyl)-piperidines having sigma and... 4-(4-fluorophenylmethyl)-piperidines having sigma and...

C - Chemistry, Metallurgy

07

D

C07D 211/22 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2140260

2140260 9426712 PCTABScor01 The present invention relates to 1,4-disubstituted piperidine derivatives of general formula (I) wherein X is hydroxymethylene or methoxymethylene, Y is a 3-membered methylene sequence and R is a p-fluorophenyl group, as well as their pharmaceutically acceptable addition salts. These compounds are useful for treating sigma receptor-related nervous system diseases.

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