C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/495 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2053980
ABSTRACT The invention relates to neuroleptic/antidepressant 4- [4- or 6-(trifluoromethyl)-2-pyridinyl]-1 piperazinyl- alkyl substituted lactam derivatives having the general structure of formula I: Image I wherein one of the groups R1 and R2 is CF3, and the other is hydrogen or CF3; R3 is hydrogen or (1-4 C) alkyl; n is an integer from 4 to 5; and m is an integer from 1 to 2; or pharmaceutically acceptable salts thereof. The invention also includes processes for making the compounds and their salts.
Carlier Patrick
Combourieu Michel
Monteil Andre Jean-Claude
Poisson Claude
Akzo N.v.
Fetherstonhaugh & Co.
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