C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/237, 260/314
C07D 235/08 (2006.01) A61K 31/415 (2006.01) C07D 235/06 (2006.01)
Patent
CA 2004911
Abstract 4,5,6,7-Tetrahydrobenzimidazole derivatives represented by general formula (I) Image (I) (wherein groups represents the following: R1, R2, R3: independently represent hydrogen atom, hydroxy group, a halogen atom, a lower alkyl group which may optionally be substituted with a halogen atom, a lower alkoxy group, a lower alkylthio group, an aralkyloxy group, an aryloxy group, a lower alkanoyl group, carboxy group, a lower alkoxycarbonyl group or nitro group; R4, R5, R6: hydrogen atom or a lower alkyl group; X : oxygen atom or sulfur atom; or salts thereof which are believed to have a 5-HT3 antagonizing activity.
Koide Tokuo
Matsuhisa Akira
Miyata Keiji
Ohta Mitsuaki
Suzuki Takeshi
Johnson Douglas S. Q.c.
Yamanouchi Pharmaceutical Co. Ltd.
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