C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/14 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 209/20 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2335711
A substituted 4-, 5-, 6-, and 7-indole or indoline derivative of Formula (I) wherein A is a group having formula (IIA), (IIB), (IIC) wherein X, U, Y, R3 to R12, Z, W, n and m are as defined above. The compounds are potent serotonin reuptake inhibitors and have 5-HT1A receptor antagonistic activity.
L'invention concerne un dérivé de 4-, 5-, 6-, et 7-indole ou d'indoline substitué de formule (I), dans laquelle A représente un groupe de formule (IIA), (IIB), (IIC), dans laquelle X, U, Y, R?3¿ à R?12¿, Z, W, n et m sont tels que définis ci-dessus. Les composés de cette invention sont de puissants inhibiteurs du recaptage de la sérotonine, et présentent une action antagoniste du récepteur 5-HT¿1A?.
Krog-Jensen Christian
Mikkelsen Ivan
Moltzen Ejner Knud
H. Lundbeck A/s
Robic
LandOfFree
4,5,6 and 7-indole and indoline derivatives, their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4,5,6 and 7-indole and indoline derivatives, their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4,5,6 and 7-indole and indoline derivatives, their... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1868162