4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-...

Details 4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-... 4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-...

C - Chemistry, Metallurgy

07

D

260/237.6

C07D 513/20 (2006.01) C07D 489/00 (2006.01) C07D 489/08 (2006.01)

Patent

CA 1218990

-14- ABSTRACT Compounds the structural formula Image or their pharmaceutically acceptable salts, wherein X is H or CH3, Z is NH2 or OR6, R1 is a C1-8 alkyl, C3-6-cycloalkylmethyl, or phenyl-C1-2alkyl group, R2 is hydrogen, hydroxy, chloro or fluoro, R3 is hydrogen, hydroxy, methoxy,-OCO-(C1-6-alkyl) or morpholinoethoxy, R4 and R5 may be the same or different and are H or C1-6alkyl, R4 is H, C1-4 alkyl, C3-5 alkenyl, C3-7 cycloalkyl phenyl, or phenyl substituted by one to three alkyl groups with a total of 4 carbon atoms are useful opiod agonists and antagonists.

450106

Affiliated with

Also associated with

Rating

4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4,5.alpha.epoxymorphinan-6-spiro-2'-(4'-carboxy,1',3'-... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1279045