4,5-dihydro-1h-pyrazole compounds and their pharmaceutical uses

Details 4,5-dihydro-1h-pyrazole compounds and their pharmaceutical uses 4,5-dihydro-1h-pyrazole compounds and their pharmaceutical uses

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2756250

Mineralocorticoid receptor antagonists (MRa), pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetic nephropathy and hypertension in mammals, including humans.

La présente invention concerne des antagonistes de récepteur minéralocorticoïde (MRa), des compositions pharmaceutiques contenant de tels inhibiteurs et l'utilisation de tels inhibiteurs pour traiter, par exemple, une néphropathie diabétique et l'hypertension chez des mammifères, comprenant les humains.

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