4,5-dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2-(3h...

Details 4,5-dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2-(3h... 4,5-dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2-(3h...

C - Chemistry, Metallurgy

07

D

260/366.1

C07D 307/32 (2006.01)

Patent

CA 1078856

ABSTRACT OF THE DISCLOSURE The invention is 4,5-dihydrofuran-2-(3H)ones of formula Image wherein R is selected from the group consisting of lower-alkyl having one to six carbon atoms, lower cycloalkyl having four to eight carbon atoms or phenyllower-alkyl consisting of benzyl, phenethyl and phenpropyl. The com- pounds are useful intermediates in the preparation of l-hydrocarbon-3,3- diphenyl-4-hydroxymethyl-2-pyrrolidinones which, in turn, are useful inter- mediates for the preparation of pharmacologically active 4-(4,4-disubsti- tutedpiperidinylmethyl)-3,3-diphenyl-2-pyrrolidinones.

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