4,5-dihydronaphth¬1,2-c|isoxazoles and derivatives thereof...

Details 4,5-dihydronaphth¬1,2-c|isoxazoles and derivatives thereof... 4,5-dihydronaphth¬1,2-c|isoxazoles and derivatives thereof...

C - Chemistry, Metallurgy

07

D

C07D 261/20 (2006.01) A61K 31/435 (2006.01) A61K 31/46 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 451/06 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2241845

4,5-Dihydronaphth[1,2-c]isoxazole derivatives of general formula (I), where A, X and n are defined herein are disclosed. Such compounds are useful as serotonin 5-HT3 antagonists. These compounds are useful for the treatment of anxiety, psychiatric disorders, nausea, vomiting and drug dependency.

4,5-dihydronaphth[1,2-c]isoxazoles et leurs dérivés, de formule générale (I), dans laquelle A, X et n sont tels que définis dans la description. Ces composés sont utiles comme antagonistes 5-HT¿3? de la sérotonine. Ces composés sont utiles pour traiter l'anxiété, les troubles psychiatriques, la nausée, les vomissements et la toxicomanie.

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