4,5-seco steroids

Details 4,5-seco steroids 4,5-seco steroids

C - Chemistry, Metallurgy

07

D

260/351.3, 260/3

C07D 317/70 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1047507

Abstract This invention describes novel 4,5-seco-steroids having the formula Image wherein A is -C=CH, -CH=CH2, -CH2CH3, or -?CH3; X1 is hydrogen, chlorine, bromine, or fluorine; R1 is hydrogen, hydroxyl, -O?-R2, chlorine, bromine, fluorine or iodine; R2 is lower alkyl; P is hydrogen, lower alkyl, or aryl; Q is lower alkyl or aryl; Y is hydrogen and Y' is hydroxyl or together Y and Y' are =O and a process for preparing these compounds which are useful as anti-inflammatory agents.

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