4(5)-substituted imidazoles

Details 4(5)-substituted imidazoles 4(5)-substituted imidazoles

C - Chemistry, Metallurgy

07

D

167/237, 260/314

C07D 233/64 (2006.01) A61K 31/415 (2006.01) C07D 233/54 (2006.01)

Patent

CA 1238640

ABSTRACT OF THE DISCLOSURE This invention as disclosed provides a process for preparing novel .alpha.,.alpha.-diphenyl-4(5)-imidazolemethanes, in which the phenyl rings in the molecule may be halo-substituted and the methane carbon may also bear an additional substituent; and the novel .alpha.,.alpha.-diphenyl-4(5)-imidazolemethanes so prepared. These compounds are useful as pharmaceuticals, and more specifically, in inhibiting aromatase and in treating or preventing estrogen-dependent diseases in mammals.

483665

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