4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chrome...

Details 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chrome... 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chrome...

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2192596

The present invention relates to 4-(6-fluoro-1,2-benzisoxazolyl)-1 -piperidinyl-propoxy-chromen-4-one derivatives having formula (I), wherein R is hydrogen or alkyl having 1 to 4 carbon atoms optionally substituted by hydroxyl, as well as their pharmaceutically acceptable addition salts, which are useful in the treatment of psychosis, schizophrenia and anxiety.

La présente invention décrit des dérivés de 4-(6-fluoro-1,2-benzisoxazolyl)-1-pipéridinyl-propoxy-chromen-4-one de formule (I), dans laquelle R représente hydrogène ou alkyle ayant de 1 à 4 atomes de carbone facultativement substitués par hydroxyle, ainsi que leurs sels d'addition pharmaceutiquement acceptables, utilisés dans le traitement des psychoses, de la schizophrénie et de l'anxiété.

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